SCHEMBL5535929

SCHEMBL5535929

O=P(O)(F)CC1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.44
CA12 O43570 3/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA9 Q16790 3/20 0.44
MMP1 P03956 2/20 0.44
MMP3 P08254 2/20 0.44
MMP8 P22894 2/20 0.44
MMP9 P14780 1/20 0.44
METAP1 P53582 1/20 0.42
FDPS P14324 1/20 0.34
EPHX1 P07099 2/20 0.33
ANPEP P15144 2/20 0.33
ERAP2 Q6P179 2/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
ALOX5 P09917 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14516801 0.98 MMP2 (0.41) MMP2CA12CA1CA2CA9
SCHEMBL2331815 0.80 METAP1 (0.50) MMP2CA12CA1CA2CA9
SCHEMBL31722865 0.80 CA12 (0.38) MMP2CA12CA1CA2CA9
Phosphoric Acid SCHEMBL11497465 0.78 METAP1 (0.48) MMP2CA12CA1CA2CA9
Water SCHEMBL7648271 0.78 METAP1 (0.48) MMP2CA12CA1CA2CA9
SCHEMBL10941895 0.78 METAP1 (0.48) MMP2CA12CA1CA2CA9
SCHEMBL6823936 0.76 METAP1 (0.47) MMP2CA12CA1CA2CA9
SCHEMBL8732595 0.76 MMP2 (0.48) MMP2CA12CA1CA2CA9
SCHEMBL6828011 0.76 METAP1 (0.47) MMP2CA12CA1CA2CA9
SCHEMBL17342201 0.73 CA2 (0.45) MMP2CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1844189-B1 Method for preparing a sampling swab SMITHS DETECTION INC (CA) 2020-10-28 EP claimed
EP-1854160-A2 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2007-11-14 EP claimed
WO-2006085319-A2 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) 2006-08-17 WO claimed
EP-3228624-A2 REDOX-ACTIVE CHROMOPHORE MOLECULES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2017-10-11 EP disclosed
EP-1854160-B1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RES & DEV (IL) 2017-06-21 EP disclosed
US-9309274-B2 Redox-active structures and devices utilizing the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2016-04-12 US disclosed
US-20150007371-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2015-01-01 US disclosed
US-8865890-B2 Redox-active structures and devices utilizing the same YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2014-10-21 US disclosed
US-20140196180-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH & DEVELOPMENT COMPANY LTD. (IL) 2014-07-10 US disclosed
US-8722879-B2 Redox-active structures and devices utilizing the same YEDA RESEARCH & DEVELOPMENT COMPANY LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) 2014-05-13 US disclosed
EP-1854160-A2 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2007-11-14 EP disclosed
US-20070258147-A1 Redox-active structures and devices utilizing the same YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 2007-11-08 US disclosed
WO-2006085319-A2 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) 2006-08-17 WO disclosed
EP-0672169-A1 BIOSENSOR FOR DETECTION OF AND DISTINGUISHING BETWEEN CHOLINESTERASES INHIBITORS ORITEST S. S R.O. (CZ) 1995-09-20 EP disclosed
WO-1994005808-A1 BIOSENSOR FOR DETECTION OF AND DISTINGUISHING BETWEEN CHOLINESTERASES INHIBITORS ORITEST S. S R.O. (CZ) 1994-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140196180-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME GPX4, GPX1, LPO MMP2 2722/4885CA12 1359/4885CA1 1521/4885
US-20150007371-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME GPX4, GPX1, LPO MMP2 2722/4885CA12 1359/4885CA1 1521/4885
US-20070258147-A1 Redox-active structures and devices utilizing the same GPX4, GPX1, LPO MMP2 2722/4885CA12 1359/4885CA1 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.