Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824082 | 0.85 | TUBB4A (0.53) | ALOX5TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4029345 | 0.84 | POLB (0.45) | CYP3A4TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5532781 | 0.82 | NPC1 (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5535769 | 0.81 | GABRP (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5531206 | 0.73 | NPC1 (0.50) | POLBNPC1RAB9AMEN1MAPT | |
| SCHEMBL5528306 | 0.72 | KMT2A (0.47) | POLBMEN1MAPTKMT2APARP14 | |
| SCHEMBL5535174 | 0.72 | MAPT (0.46) | ALOX5POLBNPC1RAB9AMEN1 | |
| SCHEMBL5528849 | 0.72 | MEN1 (0.42) | POLBNPC1RAB9AMEN1MAPT | |
| SCHEMBL3847245 | 0.70 | TUBB4A (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5532784 | 0.70 | PDE4A (0.52) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2007-07-25 | — | — | EP | claimed |
| WO-2006052712-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2006-05-18 | — | — | WO | claimed |