Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.50 |
| ▸ | MMP9 | P14780 | 12/20 | 0.50 |
| ▸ | MMP3 | P08254 | 11/20 | 0.50 |
| ▸ | MMP13 | P45452 | 10/20 | 0.50 |
| ▸ | MMP7 | P09237 | 9/20 | 0.50 |
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656824 | 0.84 | MMP9 (0.65) | MMP1MMP9MMP3MMP13MMP7 | |
| SCHEMBL7220742 | 0.80 | MMP1 (0.69) | MMP1MMP9MMP3MMP13MMP7 | |
| SCHEMBL2927653 | 0.80 | MMP9 (0.68) | MMP1MMP9MMP3MMP13MMP7 | |
| SCHEMBL1658416 | 0.79 | MMP9 (0.67) | MMP1MMP9MMP3MMP13MMP7 | |
| SCHEMBL1655602 | 0.79 | MMP9 (0.67) | MMP1MMP9MMP3MMP13MMP7 | |
| SCHEMBL7214256 | 0.79 | MMP1 (0.60) | MMP1MMP9MMP3MMP13MMP7 | |
| SCHEMBL2927874 | 0.78 | MMP9 (0.65) | MMP1MMP9MMP3MMP13MMP7 | |
| SCHEMBL1656110 | 0.78 | MMP9 (0.65) | MMP1MMP9MMP3MMP13MMP7 | |
| SCHEMBL1655650 | 0.77 | MMP9 (0.65) | MMP1MMP9MMP3MMP13MMP7 | |
| SCHEMBL1658472 | 0.77 | MMP9 (0.65) | MMP1MMP9MMP3MMP13MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768979-A1 | OCTAHYDROPYRROLO[2, 3, C]PYRIDINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008303-A1 | OCTAHYDROPYRROLO[2, 3, C]PYRIDINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-01-26 | — | — | WO | disclosed |