SCHEMBL5539351

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL694946	0.81	PKN1 (0.56)	KDM4EALDH1A1PKN1PKN2NPC1
	SCHEMBL694986	0.80	NPC1 (0.55)	TNKS2KDM4EALDH1A1PKN1PKN2
	SCHEMBL9030999	0.76	NPC1 (0.62)	KDM4EALDH1A1PKN1PKN2NPC1
	SCHEMBL5541674	0.75	ALDH1A1 (0.58)	KDM4EALDH1A1NPC1RAB9ACYP3A4
	SCHEMBL5541731	0.75	DHODH (0.39)	PDGFRBPDGFRAWNT3ATNKS2BCHE
	SCHEMBL694652	0.73	NPBWR1 (0.46)	KDM4EALDH1A1CYP3A4TP53GAA
	SCHEMBL5542508	0.71	ALDH1A1 (0.37)	WNT3ATNKS2KDM4EALDH1A1PKN1
	SCHEMBL5543777	0.71	KDM4E (0.37)	WNT3ATNKS2KDM4EALDH1A1PKN1
	SCHEMBL28830672	0.71	TNKS (0.69)	WNT3ATNKS2KDM4EALDH1A1NPC1
	SCHEMBL694892	0.69	ALOX5 (0.48)	KDM4EALDH1A1NPC1RAB9ACDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.