Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4278466 | 0.86 | LMNA (0.45) | ALDH1A1MAPTSMN1; SMN2KDM5BLMNA | |
| SCHEMBL2066277 | 0.77 | GABRP (0.40) | ALDH1A1GAAMAPTKDM5BLMNA | |
| SCHEMBL5320187 | 0.76 | LMNA (0.39) | ALDH1A1MAPTSMN1; SMN2KDM5BLMNA | |
| SCHEMBL3079818 | 0.72 | KDM5B (0.37) | ALDH1A1MAPTSMN1; SMN2KDM5BLMNA | |
| SCHEMBL2377415 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TSHRKDM5BMEN1KMT2A | |
| SCHEMBL2221402 | 0.71 | ALDH1A1 (0.48) | ALDH1A1GAATSHRMAPTSMN1; SMN2 | |
| SCHEMBL9903580 | 0.70 | ALDH1A1 (0.43) | ALDH1A1GAATSHRMAPTSMN1; SMN2 | |
| SCHEMBL2586587 | 0.69 | ALDH1A1 (0.42) | ALDH1A1GAATSHRMAPTSMN1; SMN2 | |
| SCHEMBL17560208 | 0.69 | MYC (0.41) | ALDH1A1MAPTKDM5BLMNAHTT | |
| SCHEMBL290439 | 0.68 | MAPT (0.40) | ALDH1A1GAAMAPTSMN1; SMN2KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776351-A1 | UV FILTER | MERCK PATENT GmbH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006018104-A1 | UV FILTER | MERCK PATENT GMBH (DE) | 2006-02-23 | — | — | WO | disclosed |