Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936470 | 0.87 | ALDH1A1 (0.50) | ALDH1A1CA12CA9PRSS1PRSS2 | |
| SCHEMBL9998671 | 0.81 | CXCR5 (0.49) | ALDH1A1CA12CA9PRSS1PRSS2 | |
| SCHEMBL27958078 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CA12CA9PRSS1PRSS2 | |
| SCHEMBL27173937 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CA12CA9PRSS1PRSS2 | |
| SCHEMBL27838149 | 0.77 | KDM4E (0.47) | ALDH1A1CA12CA9KDM4EMEN1 | |
| SCHEMBL3837935 | 0.76 | SLC37A4 (0.42) | ALDH1A1CA12CA9PRSS1PRSS2 | |
| SCHEMBL6889087 | 0.75 | KDM4E (0.40) | ALDH1A1CA12CA9KDM4EMEN1 | |
| SCHEMBL8459173 | 0.75 | PLK1 (0.44) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL433915 | 0.75 | ALDH1A1 (0.52) | ALDH1A1CA12CA9PRSS1PRSS2 | |
| SCHEMBL1134750 | 0.74 | SLC37A4 (0.54) | ALDH1A1CA12CA9PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1360146-B1 | PROCESS FOR THE PREPARATION OF AQUEOUS SUSPENSIONS OF ANIONIC COLLOIDAL SILICA HAVING A NEUTRAL PH AND APPLICATIONS THEREOF | AZ ELECTRONIC MATERIALS USA (US) | 2012-06-13 | — | — | EP | claimed |