Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | PRSS12 | P56730 | 11/20 | 0.52 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15283104 | 0.89 | PRSS12 (0.65) | RAB9ARXFP1PRSS12 | |
| SCHEMBL5540139 | 0.77 | PRSS12 (0.79) | PRSS12F10 | |
| SCHEMBL314749 | 0.69 | MAPK1 (0.71) | RAB9ARXFP1MAPK1PRSS12F10 | |
| SCHEMBL10246445 | 0.69 | MAPT (0.57) | RAB9ARXFP1PRSS12F10KDM4E | |
| SCHEMBL5540646 | 0.69 | PRSS12 (0.53) | PRSS12 | |
| SCHEMBL6592475 | 0.68 | MAPK1 (0.73) | MAPK1PRSS12F10 | |
| SCHEMBL31167013 | 0.68 | L3MBTL1 (0.49) | MAPK1 | |
| SCHEMBL31167016 | 0.68 | L3MBTL1 (0.49) | MAPK1 | |
| SCHEMBL10246561 | 0.67 | PRSS12 (0.67) | PRSS12F10 | |
| SCHEMBL16553854 | 0.67 | KDM4E (0.81) | RAB9ARXFP1MAPK1PRSS12F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059442-A2 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2012-05-10 | — | — | WO | disclosed |