Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786090 | 0.91 | TP53 (0.55) | MAPTALDH1A1CES2CES1TP53 | |
| SCHEMBL7326754 | 0.85 | ALOX5 (0.48) | ALOX5MAPTALDH1A1HDAC1MEN1 | |
| SCHEMBL15057017 | 0.85 | ALOX5 (0.58) | ALOX5AKR1C3MAPTALDH1A1TP53 | |
| SCHEMBL15057154 | 0.80 | ALOX5 (0.51) | ALOX5MAPTALDH1A1HDAC1MEN1 | |
| SCHEMBL1797099 | 0.80 | MAPT (0.61) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL6192945 | 0.80 | MAPT (0.61) | MAPTALDH1A1MEN1HTTKMT2A | |
| SCHEMBL214448 | 0.78 | CES2 (0.61) | ALOX5ALDH1A1CES2CES1TP53 | |
| SCHEMBL9850129 | 0.78 | ALDH1A1 (0.58) | AKR1C3MAPTALDH1A1CES2CES1 | |
| SCHEMBL1115173 | 0.77 | ALOX5 (0.48) | ALOX5MAPTALDH1A1NPC1PKM | |
| SCHEMBL11593026 | 0.76 | CES2 (0.76) | ALDH1A1CES2CES1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265106-B2 | Method for isolating (R)-tofisopam | VELA AQUISITION CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |