Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540385 | 0.91 | ALOX5 (0.52) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL1797099 | 0.89 | MAPT (0.61) | MEN1KMT2APOLBMAPTBLM | |
| SCHEMBL6192945 | 0.89 | MAPT (0.61) | MEN1KMT2APOLBMAPTBLM | |
| SCHEMBL9850129 | 0.81 | ALDH1A1 (0.58) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL9850126 | 0.81 | AKR1C3 (0.64) | TP53MEN1KMT2APOLBMAPT | |
| SCHEMBL181572 | 0.81 | CES2 (0.78) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL333455 | 0.79 | TP53 (0.73) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL8962468 | 0.79 | CES2 (0.75) | TP53CES2CES1MEN1KMT2A | |
| Hydrazine SCHEMBL28139111 | 0.78 | TP53 (0.67) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL7326754 | 0.78 | ALOX5 (0.48) | MEN1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625523-B1 | process of preparing a cis-oxalato(trans-L-1,2-cyclohexanediamine) Pt(II) complex having high optical purity | DEBIOPHARM SA (CH) | 2001-10-31 | — | — | EP | claimed |