SCHEMBL5542130

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5544689	0.87	KIF11 (0.40)	GPR3KIF11KDM4ECRHBPCRHR2
	SCHEMBL5544963	0.80	ALDH1A1 (0.41)	KDM4ENPC1RAB9ALMNACYP1A2
	SCHEMBL5544606	0.75	KIF11 (0.41)	KIF11KDM4ETRPA1
	SCHEMBL3535699	0.74	GPR3 (0.39)	GPR3KIF11KDM4ECRHBPCRHR2
	SCHEMBL5546122	0.72	—	—
	SCHEMBL5544691	0.71	NPC1 (0.41)	GPR3KIF11KDM4ECRHBPCRHR2
	SCHEMBL5542574	0.69	TRPA1 (0.35)	KIF11KDM4ENPC1RAB9ALMNA
	SCHEMBL5535303	0.69	GRM5 (0.41)	GPR3KIF11KDM4ECRHBPCRHR2
	SCHEMBL14409863	0.69	NPC1 (0.42)	GPR3KIF11KDM4ECRHBPCRHR2
	SCHEMBL5540032	0.67	NPC1 (0.42)	GPR3KIF11KDM4ECRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.