Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578089 | 0.98 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4TSHRHAO1 | |
| SCHEMBL21770055 | 0.90 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4TSHRMAOA | |
| SCHEMBL3482287 | 0.90 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4TSHRMAOA | |
| SCHEMBL6704196 | 0.90 | HAO1 (0.59) | ALDH1A1TDP1HAO1MAPTKCNH2 | |
| SCHEMBL23192020 | 0.88 | SLC18A3 (0.55) | ALDH1A1TDP1HAO1SLC18A3NFE2L2 | |
| SCHEMBL22291709 | 0.88 | SLC18A3 (0.55) | ALDH1A1TDP1HAO1SLC18A3NFE2L2 | |
| SCHEMBL21449754 | 0.88 | SLC18A3 (0.55) | ALDH1A1TDP1HAO1SLC18A3NFE2L2 | |
| SCHEMBL24096570 | 0.88 | SLC18A3 (0.55) | ALDH1A1TDP1HAO1SLC18A3NFE2L2 | |
| SCHEMBL112829 | 0.88 | SLC18A3 (0.55) | ALDH1A1TDP1HAO1SLC18A3NFE2L2 | |
| SCHEMBL7301118 | 0.88 | SLC18A3 (0.55) | ALDH1A1TDP1HAO1SLC18A3NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210382038-A1 | METHOD FOR IDENTIFYING MODULATORS OF NOTCH SIGNALING | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2021-12-09 | — | — | US | claimed |
| US-20190219566-A1 | METHOD FOR IDENTIFYING MODULATORS OF NOTCH SIGNALING | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2019-07-18 | — | — | US | claimed |
| EP-3332783-A1 | INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS | Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) | 2018-06-13 | — | — | EP | claimed |
| EP-2793884-B1 | INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2017-11-29 | — | — | EP | claimed |
| US-9296682-B2 | Inhibitors of notch signalling pathway and use thereof in treatment of cancers | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-03-29 | — | — | US | claimed |
| EP-2793884-A1 | INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS | Ecole Polytechnique Federale de Lausanne (EPFL) (CH) | 2014-10-29 | — | — | EP | claimed |
| WO-2013093885-A1 | INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2013-06-27 | — | — | WO | claimed |
| EP-3797991-B1 | PREPREG AND PRODUCTION METHOD THEREFOR, SLIT TAPE PREPREG, CARBON FIBER-REINFORCED COMPOSITE MATERIAL | TORAY INDUSTRIES (JP) | 2025-10-29 | — | — | EP | disclosed |
| US-12448510-B2 | Prepreg, method for producing same, and slit tape prepreg | TORAY INDUSTRIES, INC. (JP) | 2025-10-21 | — | — | US | disclosed |
| EP-3995536-B1 | PREPREG AND FIBER-REINFORCED COMPOSITE MATERIAL | TORAY INDUSTRIES (JP) | 2025-06-18 | — | — | EP | disclosed |
| EP-3332783-B1 | INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2024-12-04 | — | — | EP | disclosed |
| CN-119019324-A | Process for preparing aminodiaryl ethers and aminodiaryl ether hydrochlorides | 塞莱斯蒂亚生物技术股份公司 | 2024-11-26 | — | — | CN | disclosed |
| US-12030855-B2 | Process for making amino diaryl ethers and amino diaryl ethers hydrochloride salts | CELLESTIA BIOTECH AG (CH) | 2024-07-09 | — | — | US | disclosed |
| US-5928733-A | Active-matrix liquid crystal display | HITACHI, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5907005-A | SUITABLE FOR PRODUCING A LIQUID CRYSTAL ALIGNING FILM WITH SPECIFIC THICKNESS CONSISTS OF POLYAMIC ACID OR POLYIMIDE, AND A SOLVENT CONSISTS OF N-METHYL-PYRROLIDONE AND DIMETHYL IMIDAZOLIDINONE, AN ALKYL LACTATE AND AN ETHER | CHISSO CORPORATION (JP) | 1999-05-25 | — | — | US | disclosed |
| US-5798810-A | RUBBING, IRRADIATING AND SEALING | CHISSO CORPORATION (JP) | 1998-08-25 | — | — | US | disclosed |
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0113922-A2 | Process for the manufacture of cationic methine dyes | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| EP-0113921-A2 | Process for the manufacture of stable solutions of cationic methine dyes | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-3956264-A | Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210382038-A1 | METHOD FOR IDENTIFYING MODULATORS OF NOTCH SIGNALING | NOTCH3, NOTCH1, NOTCH4 | ALDH1A1 3224/4885TDP1 3305/4885CYP3A4 2750/4885 |
| US-20190219566-A1 | METHOD FOR IDENTIFYING MODULATORS OF NOTCH SIGNALING | NOTCH3, NOTCH1, NOTCH4 | ALDH1A1 3224/4885TDP1 3305/4885CYP3A4 2750/4885 |
| US-12030855-B2 | Process for making amino diaryl ethers and amino diaryl ethers hydrochloride salts | ADH1C, ADH1A, DDC | ALDH1A1 42/4885TDP1 3274/4885CYP3A4 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.