Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541479 | 0.94 | DGKA (0.53) | TP53TSHRPLA2G4BNR5A1NAAA | |
| SCHEMBL5542133 | 0.88 | PLA2G4B (0.52) | TP53TSHRPLA2G4BNR5A1NAAA | |
| SCHEMBL4457893 | 0.84 | LTA4H (0.48) | TSHR | |
| SCHEMBL77477 | 0.84 | NR5A1 (0.60) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL338316 | 0.84 | NR5A1 (0.60) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL988767 | 0.84 | NR5A1 (0.60) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL263776 | 0.84 | NR5A1 (0.60) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL9121701 | 0.84 | NR5A1 (0.60) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL987954 | 0.84 | NR5A1 (0.60) | TP53TSHRPLA2G4BNR5A1RARB | |
| SCHEMBL309133 | 0.84 | NR5A1 (0.60) | TP53TSHRPLA2G4BNR5A1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2129148-A | — | — | None | — | — | JP | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| JP-H02129148-A | CHIRAL COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AND DEVICE FOR LIQUID CRYSTAL DISPLAY | DAINIPPON INK & CHEM INC | 1990-05-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | TP53 4494/4885TSHR 319/4885PLA2G4B 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.