SCHEMBL5543342

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5546370	0.85	CYP1A2 (0.45)	CYP1A2CYP2A6KDM4EMEN1KMT2A
	SCHEMBL5543336	0.81	CYP1A2 (0.45)	CYP1A2CYP2A6KDM4EMEN1KMT2A
	SCHEMBL5544002	0.80	ALDH1A1 (0.47)	CYP1A2KDM4EMEN1KMT2AHSD17B10
	SCHEMBL5535303	0.79	GRM5 (0.41)	CYP1A2KDM4EHSD17B10GAARAB9A
	SCHEMBL8404418	0.75	CYP1A2 (0.48)	CYP1A2CYP2A6KDM4EMEN1KMT2A
	SCHEMBL19382614	0.74	CYP1A2 (0.61)	CYP1A2CYP2A6KDM4EMEN1KMT2A
	SCHEMBL2094560	0.72	CYP2A6 (0.50)	CYP1A2CYP2A6MEN1KMT2AALDH1A1
	SCHEMBL13701012	0.72	MCL1 (0.39)	CYP1A2HSD17B10TSHR
	SCHEMBL2091623	0.72	CYP1A2 (0.37)	CYP1A2CYP2A6MAPTCASP3
	SCHEMBL443070	0.71	CYP1A2 (0.79)	CYP1A2CYP2A6KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.