Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250636 | 0.98 | MTNR1A (0.56) | MTNR1AMTNR1BCALM1IDH1LTA4H | |
| SCHEMBL8099663 | 0.96 | MTNR1A (0.49) | MTNR1AMTNR1BCALM1IDH1LTA4H | |
| SCHEMBL5424543 | 0.91 | MTNR1A (0.47) | MTNR1AMTNR1BCALM1KIF11CNR1 | |
| SCHEMBL8099752 | 0.88 | MTNR1A (0.51) | MTNR1AMTNR1BCALM1IDH1DRD2 | |
| SCHEMBL8086016 | 0.87 | CALM1 (0.55) | MTNR1AMTNR1BCALM1IDH1LTA4H | |
| SCHEMBL6546128 | 0.87 | CALM1 (0.60) | CALM1IDH1LTA4HLMNASLC22A2 | |
| SCHEMBL28167259 | 0.86 | ESR1 (0.52) | MTNR1AMTNR1BIDH1CNR1CNR2 | |
| SCHEMBL8094151 | 0.86 | LPL (0.53) | MTNR1AMTNR1B | |
| SCHEMBL8095725 | 0.85 | LPL (0.54) | MTNR1AMTNR1B | |
| SCHEMBL8093587 | 0.85 | LPL (0.54) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |