Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | ATIC | P31939 | 2/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187957 | 0.81 | FBP1 (0.50) | UMPSFBP1TAS1R3TAS1R1ATIC | |
| SCHEMBL3497312 | 0.76 | PYGL (0.34) | PYGL | |
| SCHEMBL4359388 | 0.73 | FBP1 (0.53) | UMPSFBP1TAS1R3TAS1R1ATIC | |
| SCHEMBL1063228 | 0.71 | UMPS (0.49) | UMPSFBP1TAS1R3TAS1R1ATIC | |
| SCHEMBL15008514 | 0.69 | UMPS (0.54) | UMPSFBP1TAS1R3TAS1R1ATIC | |
| SCHEMBL5547964 | 0.69 | UMPS (0.54) | UMPSFBP1TAS1R3TAS1R1ATIC | |
| SCHEMBL11281748 | 0.68 | FBP1 (0.43) | UMPSFBP1TAS1R3TAS1R1IMPDH2 | |
| SCHEMBL27789884 | 0.68 | FBP1 (0.51) | UMPSFBP1TAS1R3TAS1R1ATIC | |
| SCHEMBL2936680 | 0.67 | ATIC (0.54) | FBP1TAS1R3TAS1R1ATICP2RY12 | |
| SCHEMBL31338629 | 0.67 | ATIC (0.53) | UMPSFBP1TAS1R3TAS1R1ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490678-A4 | COMPOSITIONS AND METHODS FOR MODELING BACILLUS SUBTILIS METABOLISM | GENOMATICA INC (US) | 2007-01-03 | — | — | EP | disclosed |
| EP-1490678-A2 | COMPOSITIONS AND METHODS FOR MODELING BACILLUS SUBTILIS METABOLISM | Genomatica, Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003081207-A2 | COMPOSITIONS AND METHODS FOR MODELING BACILLUS SUBTILIS METABOLISM | GENOMATICA, INC. (US) | 2003-10-02 | — | — | WO | disclosed |