Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 9/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 8/20 | 0.56 |
| ▸ | DRD2 | P14416 | 8/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.56 |
| ▸ | DRD4 | P21917 | 8/20 | 0.56 |
| ▸ | DRD3 | P35462 | 8/20 | 0.56 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542098 | 0.96 | CHRM1 (0.52) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL5537268 | 0.94 | CHRM1 (0.51) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL5539807 | 0.91 | ATAD2 (0.52) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL5534846 | 0.85 | ATAD2 (0.68) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL5544599 | 0.84 | DRD2 (0.58) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL5542111 | 0.80 | DRD2 (0.53) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL6200847 | 0.79 | DRD2 (0.84) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL5537272 | 0.79 | DRD2 (0.52) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL14049826 | 0.79 | GRIN1 (0.57) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL5543650 | 0.77 | CYP11B2 (0.51) | ATAD2CYP1A2CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | CHRM1 463/4885CHRM2 862/4885CHRM4 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.