Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | DRD4 | P21917 | 7/20 | 0.58 |
| ▸ | DRD3 | P35462 | 7/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.58 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542111 | 0.96 | DRD2 (0.53) | DRD2DRD4DRD3CHRM1CHRM2 | |
| SCHEMBL5537272 | 0.94 | DRD2 (0.52) | DRD2DRD4DRD3CHRM1CHRM2 | |
| SCHEMBL5539818 | 0.91 | ATAD2 (0.54) | DRD2DRD4DRD3CHRM1CHRM2 | |
| SCHEMBL4100824 | 0.87 | GRIN1 (0.49) | DRD2DRD4DRD3CHRM1CHRM2 | |
| SCHEMBL1763836 | 0.86 | GRIN1 (0.51) | DRD2DRD4DRD3CHRM1CHRM2 | |
| SCHEMBL435242 | 0.84 | ATAD2 (0.69) | DRD2DRD4DRD3CHRM1CHRM2 | |
| SCHEMBL5544590 | 0.84 | CHRM1 (0.56) | DRD2DRD4DRD3CHRM1CHRM2 | |
| SCHEMBL8005017 | 0.84 | ATAD2 (0.49) | DRD2DRD4DRD3CHRM1CHRM2 | |
| SCHEMBL4103777 | 0.83 | CHRM1 (0.75) | DRD2DRD4DRD3CHRM1CHRM2 | |
| SCHEMBL27619331 | 0.81 | DRD2 (0.51) | DRD2DRD4DRD3CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | DRD2 542/4885DRD4 368/4885DRD3 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.