SCHEMBL5545508

SCHEMBL5545508

CNCCNCc1ccccn1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.66
HRH3 Q9Y5N1 1/20 0.65
LMNA P02545 3/20 0.62
ALOX15 P16050 3/20 0.62
ALDH1A1 P00352 3/20 0.62
TAAR1 Q96RJ0 1/20 0.62
SCN8A Q9UQD0 1/20 0.55
TDP1 Q9NUW8 1/20 0.54
SIRT2 Q8IXJ6 1/20 0.53
KDM4E B2RXH2 2/20 0.51
TSHR P16473 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
HTR2A P28223 1/20 0.48
HTR2C P28335 1/20 0.48
CYP1A2 P05177 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348655 0.90 CHRM2 (0.78) CHRM2HRH3LMNAALOX15ALDH1A1
SCHEMBL6205124 0.89 CHRM2 (0.72) CHRM2HRH3LMNAALOX15ALDH1A1
SCHEMBL284677 0.88 CHRM2 (0.81) CHRM2HRH3LMNAALOX15ALDH1A1
SCHEMBL3071526 0.88 CHRM2 (0.81) CHRM2HRH3LMNAALOX15ALDH1A1
SCHEMBL9777412 0.86 CHRM2 (0.79) CHRM2HRH3LMNAALOX15ALDH1A1
Hydrochloric Acid SCHEMBL9702944 0.86 CHRM2 (0.79) CHRM2HRH3LMNAALOX15ALDH1A1
Hydrochloric Acid SCHEMBL3626828 0.86 CHRM2 (0.79) CHRM2HRH3LMNAALOX15ALDH1A1
SCHEMBL7004091 0.84 HRH3 (0.79) CHRM2HRH3LMNAALOX15ALDH1A1
SCHEMBL434742 0.83 CHRM2 (0.68) CHRM2HRH3LMNAALOX15ALDH1A1
SCHEMBL9188072 0.83 CHRM2 (0.86) CHRM2HRH3LMNAALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104704008-B Water insoluble copolymers comprising pendant aryl epoxide groups 罗门哈斯公司 2016-10-26 CN claimed
US-9321871-B2 Water insoluble copolymer including pendant aryl epoxide groups DOW GLOBAL TECHNOLOGIES LLC 2016-04-26 US claimed
US-20150259456-A1 WATER INSOLUBLE COPOLYMER INCLUDING PENDANT ARYL EPOXIDE GROUPS ROHM AND HAAS CHEMICALS LLC 2015-09-17 US claimed
CN-104704008-A Water insoluble copolymers comprising pendant aryl epoxide groups ROHM & HAAS 2015-06-10 CN claimed
US-20230346769-A1 USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA UNIVERSIDAD DE GRANADA (ES) 2023-11-02 US disclosed
US-20230346769-A1 USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA UNIVERSIDAD DE GRANADA (ES) 2023-11-02 US disclosed
US-20230346769-A1 USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA UNIVERSIDAD DE GRANADA (ES) 2023-11-02 US disclosed
EP-4180039-A1 <SMALLCAPS/>? ? ?LEISHMANIA? ? ? ? ?USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS Universidad de Granada (ES) 2023-05-17 EP disclosed
EP-4180039-A1 <SMALLCAPS/>? ? ?LEISHMANIA? ? ? ? ?USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS Universidad de Granada (ES) 2023-05-17 EP disclosed
WO-2022008784-A1 USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA UNIVERSIDAD DE GRANADA (ES) 2022-01-13 WO disclosed
US-9321871-B2 Water insoluble copolymer including pendant aryl epoxide groups DOW GLOBAL TECHNOLOGIES LLC 2016-04-26 US disclosed
US-9187588-B2 Elution of metal ions from chelating resin using amino acid eluant DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-17 US disclosed
US-6187478-B1 ENHANCED ACTIVE MATERIAL UTILIZATION EFFICIENCY AND UTILIZATION OF SULFURIC ACID ELECTROLYTE NECESSARY FOR DISCHARGE REACTION OF LEAD ACID BATTERY ENSCI INC 2001-02-13 US disclosed
US-6168886-B1 CAPACITY MAINTENANCE ENSCI INC 2001-01-02 US disclosed
US-6132901-A Battery element containing efficiency improving additives ENSCI INC (US) 2000-10-17 US disclosed
US-4098867-A WATER-INSOLUBLE CHELATE EXCHANGE RESINS FROM AMINOPYRIDINES AND PROCESS FOR THE SELECTIVE EXTRACTION OF VALUABLE METALS USING THE SAME THE DOW CHEMICAL COMPANY (US) 1978-07-04 US disclosed
US-4098867-A WATER-INSOLUBLE CHELATE EXCHANGE RESINS FROM AMINOPYRIDINES AND PROCESS FOR THE SELECTIVE EXTRACTION OF VALUABLE METALS USING THE SAME THE DOW CHEMICAL COMPANY (US) 1978-07-04 US disclosed
US-4031038-A Water insoluble chelate exchange resins having a crosslinked polymer matrix and pendant thereto a plurality of methyleneaminopyridine groups THE DOW CHEMICAL COMPANY (US) 1977-06-21 US disclosed
US-4031038-A Water insoluble chelate exchange resins having a crosslinked polymer matrix and pendant thereto a plurality of methyleneaminopyridine groups THE DOW CHEMICAL COMPANY (US) 1977-06-21 US disclosed
US-3998924-A Recovery of non-ferrous metals from acidic liquors with a chelate exchange resin in presence of iron(III) THE DOW CHEMICAL COMPANY (US) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346769-A1 USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA SRM, SMS, ARG2 CHRM2 1038/4885HRH3 378/4885LMNA 1805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.