Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790494 | 0.82 | GABRA1 (0.44) | GABRA1GABRB2ADRA2AADRA2BADRA2C | |
| SCHEMBL1010572 | 0.82 | GABRA1 (0.46) | GABRA1GABRB2ADRA2AADRA2BADRA2C | |
| SCHEMBL28307193 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2ADRA2AADRA2BADRA2C | |
| SCHEMBL5586090 | 0.78 | GABRA1 (0.41) | GABRA1GABRB2ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL27436289 | 0.77 | ADRA2A (0.41) | GABRA1GABRB2ADRA2AADRA2BADRA2C | |
| SCHEMBL8997142 | 0.77 | ADRA2A (0.41) | GABRA1GABRB2ADRA2AADRA2BADRA2C | |
| SCHEMBL18800169 | 0.77 | HTR1D (0.34) | CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16170099 | 0.75 | SCN4A (0.43) | GABRA1GABRB2SCN4ALMNASCN1A | |
| SCHEMBL9715056 | 0.74 | KDM4E (0.51) | GABRA1GABRB2GAALMNATSHR | |
| SCHEMBL985213 | 0.74 | TSHR (0.44) | GABRA1GABRB2ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242221-B2 | Half-metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-08-14 | — | — | US | disclosed |
| US-20120108764-A1 | HALF-METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-05-03 | — | — | US | disclosed |
| US-8110640-B2 | Half-metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-02-07 | — | — | US | disclosed |
| US-8110640-B2 | Half-metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-02-07 | — | — | US | disclosed |
| US-20110065874-A1 | HALF-METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-03-17 | — | — | US | disclosed |
| US-20110065874-A1 | HALF-METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-03-17 | — | — | US | disclosed |
| US-7884165-B2 | polymerization coordination catalysts comprising metal complex of zirconium, titanium, or hafnium having (substituted) cyclopentadienyl, indenyl, and/or fluorenyl groups; and organoaluminum halide, hydride and/or hydroxide; fluorided alumina-silica catalyst support | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-02-08 | — | — | US | disclosed |
| US-7884165-B2 | polymerization coordination catalysts comprising metal complex of zirconium, titanium, or hafnium having (substituted) cyclopentadienyl, indenyl, and/or fluorenyl groups; and organoaluminum halide, hydride and/or hydroxide; fluorided alumina-silica catalyst support | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-02-08 | — | — | US | disclosed |
| US-20100010174-A1 | HALF-METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100010174-A1 | HALF-METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010174-A1 | HALF-METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | POLM, OPRM1, AP2M1 | GABRA1 3555/4885GABRB2 3836/4885ADRA2A 4353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.