Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790494 | 0.82 | GABRA1 (0.44) | ADRA2AADRA2BADRA2CGABRA1GABRB2 | |
| SCHEMBL5586090 | 0.78 | GABRA1 (0.41) | ADRA2AADRA2BADRA2CGABRA1GABRB2 | |
| SCHEMBL5547437 | 0.77 | GABRA1 (0.40) | ADRA2AADRA2BADRA2CGABRA1GABRB2 | |
| SCHEMBL9715056 | 0.74 | KDM4E (0.51) | GABRA1GABRB2GAAMEN1KMT2A | |
| SCHEMBL985213 | 0.74 | TSHR (0.44) | ADRA2AADRA2BADRA2CGABRA1GABRB2 | |
| SCHEMBL9356930 | 0.74 | ALDH1A1 (0.49) | ADRA2AADRA2BADRA2CGABRA1GABRB2 | |
| SCHEMBL8961940 | 0.74 | ALDH1A1 (0.47) | ADRA2AADRA2BADRA2CKDM4ELMNA | |
| SCHEMBL29699897 | 0.74 | ALDH1A1 (0.47) | ADRA2AADRA2BADRA2CKDM4ELMNA | |
| SCHEMBL9625893 | 0.73 | ALDH1A1 (0.43) | ADRA2AADRA2BADRA2CKDM4ELMNA | |
| SCHEMBL7805020 | 0.73 | PTGER4 (0.53) | GAAKDM4ESCN4AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530442-B1 | Process for producing a hydroxy-substituted poly (phenylene ether) resin | MITSUBISHI CHEM CORP (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5266673-A | Compatibilizer for polymer blends and alloys | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0530442-A1 | Process for producing a hydroxy-substituted poly (phenylene ether) resin | MITSUBISHI CHEMICAL CORPORATION (JP) | 1993-03-10 | — | — | EP | disclosed |
| EP-0517017-A2 | Thermoplastic resin composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-12-09 | — | — | EP | disclosed |