Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 6/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540904 | 0.86 | KDM4E (0.42) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL10495624 | 0.82 | APP (0.57) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL5591719 | 0.81 | TNF (0.42) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL5598274 | 0.78 | TNF (0.60) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL27873736 | 0.75 | RAB9A (0.49) | KDM4ENPC1RAB9AKMT2ACYP19A1 | |
| SCHEMBL10505563 | 0.73 | KDM4E (0.56) | KDM4ENPC1RAB9AARKMT2A | |
| SCHEMBL5591820 | 0.72 | ALDH1A1 (0.47) | KDM4ENPC1RAB9AKMT2AIDO1 | |
| SCHEMBL4729573 | 0.72 | RAB9A (1.00) | KDM4ENPC1RAB9AKMT2AMAPT | |
| SCHEMBL5591755 | 0.71 | PIK3CD (0.42) | NPC1RAB9AKMT2A | |
| SCHEMBL212081 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1780211-A2 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1775295-A1 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-04-18 | — | — | EP | disclosed |