Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | APP | P05067 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | GLA | P06280 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MMP9 | P14780 | 2/20 | 0.66 |
| ▸ | MMP8 | P22894 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.60 |
| ▸ | TNF | P01375 | 1/20 | 0.60 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994279 | 0.90 | RAB9A (0.84) | RAB9ANPC1KDM4EAPPMAPT | |
| SCHEMBL366824 | 0.88 | RAB9A (0.81) | RAB9ANPC1KDM4EAPPMAPT | |
| SCHEMBL29474819 | 0.88 | RAB9A (0.81) | RAB9ANPC1KDM4EAPPMAPT | |
| SCHEMBL25547107 | 0.87 | NPC1 (0.77) | RAB9ANPC1KDM4EAPPMAPT | |
| SCHEMBL25543975 | 0.87 | RAB9A (0.77) | RAB9ANPC1KDM4EAPPMAPT | |
| SCHEMBL24295138 | 0.86 | RAB9A (0.79) | RAB9ANPC1KDM4EAPPMAPT | |
| 2-Phenylbenzo[D]Thiazole SCHEMBL30988131 | 0.86 | RAB9A (0.75) | RAB9ANPC1KDM4EAPPMAPT | |
| 2-Phenylbenzo[D]Thiazole SCHEMBL94005 | 0.86 | RAB9A (0.75) | RAB9ANPC1KDM4EAPPMAPT | |
| SCHEMBL4593799 | 0.85 | NPC1 (0.73) | RAB9ANPC1KDM4EAPPMAPT | |
| 2-Phenylbenzo[D]Thiazole SCHEMBL2453217 | 0.84 | RAB9A (0.72) | RAB9ANPC1KDM4EAPPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019607-B1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INT (FR) | 2024-05-15 | — | — | EP | disclosed |
| US-20240052235-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2024-02-15 | — | — | US | disclosed |
| CN-116783168-A | Electrochromic compounds and optical articles comprising the same | 依视路国际公司 | 2023-09-19 | — | — | CN | disclosed |
| US-20220332712-A1 | HETEROARYL-PYRIDINIUM COMPOUND AND REDOX FLOW BATTERY COMPRISING THE SAME | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2022-10-20 | — | — | US | disclosed |
| WO-2022136020-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022136020-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2022-06-30 | — | — | WO | disclosed |
| EP-4019607-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2022-06-29 | — | — | EP | disclosed |
| EP-4019607-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021110890-A1 | PYRIDINIUM DERIVATIVES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2021-06-10 | — | — | WO | disclosed |
| CN-103588794-B | A kind of univalent copper complex luminescent material and its preparation method | CHINA JILIANG UNIVERSITY (CN) | 2016-06-01 | — | — | CN | disclosed |
| CN-103992291-B | Method for synthesizing 2-substituted benzothiazole derivative | NANJING TECH UNIVERSITY (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-103450111-B | Green synthesis method of benzothiazole heterocyclic compound | UNIV WENZHOU | 2015-07-08 | — | — | CN | disclosed |
| CN-103992291-A | Method for synthesizing 2-substituted benzothiazole derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2014-08-20 | — | — | CN | disclosed |
| CN-103450111-A | Green synthesis method of benzothiazole heterocyclic compound | UNIV WENZHOU | 2013-12-18 | — | — | CN | disclosed |
| US-20120263646-A1 | IMAGING AGENTS AND THEIR USE FOR THE DIAGNOSTIC IN VIVO OF NEURODEGENERATIVE DISEASES, NOTABLY ALZHEIMER'S DISEASE AND DERIVATIVE DISEASES | GUERBET (FR) | 2012-10-18 | — | — | US | disclosed |
| WO-2008021210-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | CHDI, INCORPORATED | 2008-02-21 | — | — | US | disclosed |
| US-5874431-A | ANTITUMOR AGENTS; BREAST CANCER | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-02-23 | — | — | US | disclosed |
| US-5849765-A | Tetrahydropyridine derivatives as dopamine receptor subtype ligands | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240052235-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | EYA3, LAGE3, CDKL5 | RAB9A 2687/4885NPC1 4449/4885KDM4E 1272/4885 |
| US-20120263646-A1 | IMAGING AGENTS AND THEIR USE FOR THE DIAGNOSTIC IN VIVO OF NEURODEGENERATIVE DISEASES, NOTABLY ALZHEIMER'S DISEASE AND DERIVATIVE DISEASES | SNCA, PSEN2, CLN6 | RAB9A 496/4885NPC1 30/4885KDM4E 4711/4885 |
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | HTT, SNCA, NLN | RAB9A 2207/4885NPC1 78/4885KDM4E 3242/4885 |
| US-20220332712-A1 | HETEROARYL-PYRIDINIUM COMPOUND AND REDOX FLOW BATTERY COMPRISING THE SAME | NOX4, DUOX1, PNPO | RAB9A 1298/4885NPC1 4380/4885KDM4E 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.