SCHEMBL5547819

SCHEMBL5547819

CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC[C@@H](N)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.61
CA5A P35218 1/20 0.61
CTSL P07711 4/20 0.59
CTSS P25774 4/20 0.59
CA1 P00915 1/20 0.59
CTSB P07858 5/20 0.57
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
CTSD P07339 2/20 0.55
CTSK P43235 4/20 0.53
CASP3 P42574 2/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
CASP9 P55211 1/20 0.53
CASP6 P55212 1/20 0.53
CASP8 Q14790 1/20 0.53
LMNA P02545 1/20 0.52
ELANE P08246 1/20 0.51
PRTN3 P24158 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5547827 1.00 CA2 (0.61) CA2CA5ACTSLCTSSCA1
SCHEMBL5662889 1.00 CA2 (0.61) CA2CA5ACTSLCTSSCA1
SCHEMBL5547822 1.00 CA2 (0.61) CA2CA5ACTSLCTSSCA1
SCHEMBL4075762 0.86 CTSS (0.65) CA2CA5ACTSLCTSSCA1
SCHEMBL16488980 0.85 CTSL (0.59) CA2CA5ACTSLCTSSCA1
SCHEMBL15289789 0.85 CTSL (0.59) CA2CA5ACTSLCTSSCA1
SCHEMBL16488984 0.85 CTSL (0.59) CA2CA5ACTSLCTSSCA1
SCHEMBL15289840 0.85 CTSL (0.59) CA2CA5ACTSLCTSSCA1
SCHEMBL14401772 0.85 CTSD (0.71) CA2CA5ACTSLCTSSCA1
SCHEMBL11672300 0.85 CTSD (0.71) CA2CA5ACTSLCTSSCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1770085-A1 DIAMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME AND FUNGICIDE CONTAINING THE DERIVATIVE AS ACTIVE INGREDIENT Mitsui Chemicals, Inc. (JP) 2007-04-04 EP disclosed