Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | STK3 | Q13188 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25636281 | 0.81 | NCF1 (0.49) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL2876594 | 0.74 | NR4A2 (0.56) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL30604782 | 0.74 | NR4A2 (0.56) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL485347 | 0.74 | NCF1 (0.51) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL29862680 | 0.74 | NCF1 (0.51) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL20524033 | 0.74 | NCF1 (0.48) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL11662073 | 0.73 | HTR2C (0.42) | — | |
| SCHEMBL9033424 | 0.73 | PSMD14 (0.62) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL16248304 | 0.73 | NCF1 (0.52) | NCF1PARP1NR1H2NR1H3GSK3A | |
| SCHEMBL8366944 | 0.72 | NR1H2 (0.51) | NCF1PARP1NR1H2NR1H3GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678180-B1 | SUBSTITUTED 2H-[1,2,4]TRIAZOLO 4,3-A PYRAZINES AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2007-08-08 | — | — | EP | disclosed |