Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.33 |
| ▸ | INMT | O95050 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30793937 | 0.80 | LMNA (0.35) | — | |
| SCHEMBL28730458 | 0.76 | MEN1 (0.30) | INMT | |
| SCHEMBL23853300 | 0.76 | INMT (0.32) | AVPR2INMTAVPR1A | |
| SCHEMBL23853303 | 0.76 | INMT (0.32) | AVPR2INMTAVPR1A | |
| SCHEMBL15392276 | 0.72 | LMNA (0.33) | INMT | |
| SCHEMBL16582952 | 0.72 | LMNA (0.33) | INMT | |
| SCHEMBL26134376 | 0.71 | OPRK1 (0.30) | — | |
| SCHEMBL22468401 | 0.69 | LMNA (0.35) | INMT | |
| SCHEMBL22468402 | 0.69 | LMNA (0.35) | INMT | |
| SCHEMBL3657559 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265109-B2 | Thiazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-20050038073-A1 | Thiazole derivatives | HOFFMAN-LA ROCHE INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038073-A1 | Thiazole derivatives | NPY4R, NPY1R, NPY2R | AVPR2 134/4885INMT 1639/4885AVPR1A 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.