Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | INMT | O95050 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22468401 | 1.00 | LMNA (0.35) | LMNASMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL23853300 | 0.94 | INMT (0.32) | LMNAINMT | |
| SCHEMBL23853303 | 0.94 | INMT (0.32) | LMNAINMT | |
| SCHEMBL29356093 | 0.71 | ALDH1A1 (0.36) | LMNAINMT | |
| SCHEMBL28730458 | 0.71 | MEN1 (0.30) | SMN1; SMN2MEN1TSHRKMT2AINMT | |
| SCHEMBL26134376 | 0.69 | OPRK1 (0.30) | — | |
| SCHEMBL5548591 | 0.69 | AVPR2 (0.33) | INMT | |
| SCHEMBL59155 | 0.69 | — | — | |
| SCHEMBL19514647 | 0.69 | — | — | |
| SCHEMBL30468382 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941922-A1 | INHIBITORS OF RAF KINASES | Kinnate Biopharma Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020198058-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2020-10-01 | — | — | WO | disclosed |