Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946390 | 0.81 | KCNH2 (0.40) | CYP8B1SLC2A1KCNH2 | |
| SCHEMBL13238486 | 0.78 | DRD2 (0.46) | CYP8B1KCNH2 | |
| SCHEMBL2955854 | 0.77 | KCNH2 (0.38) | CYP8B1KCNH2 | |
| SCHEMBL1224706 | 0.75 | CYP8B1 (0.44) | CYP8B1 | |
| SCHEMBL5548598 | 0.74 | KCNH2 (0.39) | SLC2A1KCNH2 | |
| SCHEMBL4047163 | 0.73 | CYP8B1 (0.47) | CYP8B1SLC2A1KCNH2 | |
| SCHEMBL4054921 | 0.73 | CYP8B1 (0.45) | CYP8B1SLC2A1KCNH2 | |
| SCHEMBL5740250 | 0.68 | KCNH2 (0.35) | SLC2A1KCNH2 | |
| SCHEMBL1223922 | 0.68 | NCF1 (0.40) | CYP8B1SLC2A1KCNH2 | |
| SCHEMBL2951476 | 0.67 | KCNH2 (0.51) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846411-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006081289-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-08-03 | — | — | WO | disclosed |