Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549023 | 0.83 | ADORA1 (0.38) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL5549009 | 0.78 | GSK3A (0.43) | LMNAMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL5548616 | 0.77 | CA12 (0.40) | LMNAALDH1A1TSHRGAAADORA1 | |
| SCHEMBL3528837 | 0.77 | GSK3B (0.47) | ADORA1 | |
| SCHEMBL5548893 | 0.77 | GSK3A (0.49) | LMNAKMT2ATSHRATMADORA1 | |
| SCHEMBL5550039 | 0.76 | GSK3A (0.46) | LMNAMEN1KMT2ATP53MAPT | |
| SCHEMBL5549416 | 0.76 | PDE5A (0.40) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL5549007 | 0.76 | KMT2A (0.51) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL5543068 | 0.76 | SMN1; SMN2 (0.41) | LMNAMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL5545002 | 0.76 | GSK3A (0.51) | ADORA1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678180-B1 | SUBSTITUTED 2H-[1,2,4]TRIAZOLO 4,3-A PYRAZINES AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2007-08-08 | — | — | EP | disclosed |