Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768664 | 0.85 | ADRA1D (0.52) | ADRA1DKMT2AMKNK1MKNK2ATM | |
| SCHEMBL2892390 | 0.85 | ALDH1A1 (0.47) | ADRA1DKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12109847 | 0.83 | ADRA1D (0.51) | ADRA1DKMT2AMKNK1MKNK2SMN1; SMN2 | |
| SCHEMBL30463143 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| SCHEMBL543139 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| Hydrochloric Acid SCHEMBL28203917 | 0.79 | NPC1 (0.42) | ADRA1DSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9202628 | 0.79 | ADRA1D (0.48) | ADRA1DKMT2ANFKB1TSHR | |
| SCHEMBL6129594 | 0.79 | PLA2G2A (0.56) | ADRA1DKMT2ANPC1RAB9AATM | |
| SCHEMBL16230316 | 0.78 | MAPT (0.47) | MKNK1MKNK2HPGDMAPTKDM4E | |
| SCHEMBL23931758 | 0.77 | MKNK2 (0.49) | ADRA1DKMT2AMKNK1MKNK2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |