SCHEMBL5550

SCHEMBL5550

[C]1=NOc2ccccc2C1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
OXTR P30559 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
ITGB2 P05107 1/20 0.32
ICAM1 P05362 1/20 0.32
ITGAL P20701 1/20 0.32
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4623471 0.76 MEN1 (0.34) KMT2A
SCHEMBL8588488 0.71 MAOA (0.35) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL656647 0.71 MAOA (0.35) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL655067 0.68 MAOA (0.33) MAOAMAOB
SCHEMBL3074959 0.67 MAOA (0.50) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL105430 0.67 MAOA (0.39) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL3928581 0.67 MAOA (0.39) MAOAMAOBOXTRABCG2ITGB2
SCHEMBL3128 0.65
SCHEMBL757859 0.65
SCHEMBL2851479 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18711 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271794-A Thermosetting epoxy resin composition, and prepreg, laminated board and printed circuit board comprising thermosetting epoxy resin composition 广东生益科技股份有限公司 2024-07-02 CN claimed
CN-112654621-B Substituted naphthyridinone compounds useful as T cell activators 百时美施贵宝公司 2024-05-14 CN claimed
US-11975106-B2 Uses of halogenated xanthenes in oncology and virology PROVECTUS PHARMATECH, INC. (US) 2024-05-07 US claimed
CN-117986505-A Modified dicyclopentadiene based resins 南亚塑胶工业股份有限公司 2024-05-07 CN claimed
CN-117835718-A White light organic electroluminescent composition and application thereof 深圳大学 2024-04-05 CN claimed
EP-4330246-A1 HALO-SUBSTITUTED AMINO AZA-HETEROARYL COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) Ontario Institute for Cancer Research (OICR) (CA) 2024-03-06 EP claimed
CN-117597336-A Halogen substituted amino aza-heteroaryl compounds as inhibitors of hematopoietic progenitor kinase 1 (HPK 1) 安大略省癌症研究所(OICR) 2024-02-23 CN claimed
CN-116494149-B Preparation process of ceramic resin bonding agent diamond grinding wheel 海安玻克超硬材料有限公司 2023-12-26 CN claimed
CN-117263926-A Tripterenyl-containing benzoxazine derivative, polymer, preparation method and application thereof 成都科宜高分子科技有限公司 2023-12-22 CN claimed
CN-117263999-A Camptothecin prodrugs and pharmaceutical compositions thereof 天津和美奥康医药科技有限公司 2023-12-22 CN claimed
CN-1065659-A The insecticides of N-phenylcarbamate compound, its preparation method and control harmful organism ISHIHARA SANGYO KAISHA (JP) 1992-10-28 CN claimed
EP-0498396-A2 N-phenylcarbamate compound, process for preparing the same and biocidal composition for control of harmful organisms ISHIHARA SANGYO KAISHA, Ltd. (JP) 1992-08-12 EP claimed
WO-1992011265-A1 OXO-TETRAHYDROPYRIDAZINYL-PYRAZOLO[4,3-b]-1,4-BENZOXAZINES ORTHO PHARMACEUTICAL CORPORATION (US) 1992-07-09 WO claimed
EP-0428339-A2 Heterocyclic compounds ZENECA LIMITED (GB) 1991-05-22 EP claimed
EP-0424832-A2 Carbapenem compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-05-02 EP claimed
EP-0280951-A1 Amino-propanol derivatives, process for their preparation and medicines containing these compounds, as well as intermediates Roche Diagnostics GmbH (DE) 1988-09-07 EP claimed
US-4766118-A CARDIOTONIC AGENTS, PHOSPHODIESTERASE INHIBITORS ORTHO PHARMACEUTICAL CORPORATION (US) 1988-08-23 US claimed
US-4505910-A Amino-pyrimidine derivatives, compositions and use AMERICAN HOME PRODUCTS CORPORATION (US) 1985-03-19 US claimed
EP-0130735-A1 Amino-pyrimidine derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1985-01-09 EP claimed
US-4172197-A BACTERICIDES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-10-23 US claimed