Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 9/20 | 0.56 |
| ▸ | SELE | P16581 | 9/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.56 |
| ▸ | CDK8 | P49336 | 4/20 | 0.56 |
| ▸ | CCNC | P24863 | 3/20 | 0.56 |
| ▸ | GSK3A | P49840 | 5/20 | 0.55 |
| ▸ | GSK3B | P49841 | 5/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.55 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 4/20 | 0.43 |
| ▸ | PRKACA | P17612 | 4/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29831616 | 1.00 | ICAM1 (0.56) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL17080828 | 0.84 | ICAM1 (0.51) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL30430905 | 0.84 | ICAM1 (0.51) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL15910879 | 0.84 | PIM1 (0.59) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL660155 | 0.83 | CSNK1D (0.63) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL30744198 | 0.83 | CSNK1D (0.63) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL7060300 | 0.83 | ICAM1 (0.57) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL18105584 | 0.83 | ICAM1 (0.53) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL660279 | 0.82 | ICAM1 (0.66) | ICAM1SELEVCAM1CDK8CCNC | |
| SCHEMBL20319560 | 0.82 | ICAM1 (0.41) | ICAM1SELEVCAM1CDK8CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220365-A1 | Cell adhesion-inhibiting antiinflammatory compounds | STEWART ANDREW O (US) | 2003-11-27 | — | — | US | claimed |
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | claimed |
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ABBVIE INC. | 2001-09-06 | — | — | US | claimed |
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | claimed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | claimed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | claimed |
| US-12612414-B2 | Nitrile SUMO inhibitors and uses thereof | CIT THERAPEUTICS, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-20250049035-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2025-02-13 | — | — | US | disclosed |
| US-20240360148-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | CIT THERAPEUTICS LLC | 2024-10-31 | — | — | US | disclosed |
| EP-4448534-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | Syngenta Crop Protection AG (CH) | 2024-10-23 | — | — | EP | disclosed |
| EP-3558969-B1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-18 | — | — | EP | disclosed |
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2024-09-03 | — | — | US | disclosed |
| CN-118546154-A | CDK inhibitors | 上海齐鲁制药研究中心有限公司 | 2024-08-27 | — | — | CN | disclosed |
| US-6579882-B2 | Thieno(2,3-d)pyrimidine derivatives | ABBOTT LABORATORIES | 2003-06-17 | — | — | US | disclosed |
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ABBVIE INC. | 2001-09-06 | — | — | US | disclosed |
| US-6232320-B1 | THIENO(2,3-C)PYRIDINE AND 5H-THIENO(2,3-C)PYRAN DERIATIVES | ABBOTT LABORATORIES | 2001-05-15 | — | — | US | disclosed |
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ICAM1, VCAM1, EPCAM | ICAM1 1/4885SELE 16/4885VCAM1 2/4885 |
| US-20250049035-A1 | MICROBIOCIDAL BICYCLE HETEROCYCLIC DERIVATIVES | NOX1, CASP1, CYP1A1 | ICAM1 899/4885SELE 2427/4885VCAM1 2026/4885 |
| US-20240360148-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | SUMO1, SUMO3, SUMO2 | ICAM1 1326/4885SELE 2792/4885VCAM1 2451/4885 |
| US-12612414-B2 | Nitrile SUMO inhibitors and uses thereof | SUMO1, SUMO3, PSMB6 | ICAM1 2789/4885SELE 4424/4885VCAM1 2470/4885 |
| US-20030220365-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ICAM1, VCAM1, EPCAM | ICAM1 1/4885SELE 16/4885VCAM1 2/4885 |
| US-12077521-B2 | Pyrazole derivatives as MALT1 inhibitors | MALT1, PPP3R1, SQSTM1 | ICAM1 2838/4885SELE 4772/4885VCAM1 2140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.