SCHEMBL5551748

SCHEMBL5551748

CC(C)(C)Oc1ccc(-c2c3ccccc3c(Br)c3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.41
PPARG P37231 3/20 0.36
PPARA Q07869 3/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
PPARD Q03181 1/20 0.36
ACHE P22303 3/20 0.36
RIPK1 Q13546 1/20 0.35
PTPN1 P18031 1/20 0.33
KDM4E B2RXH2 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ACP1 P24666 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5551754 0.80 ACHE (0.53) ACHEKDM4EHPGDHTTMAPT
SCHEMBL3000291 0.79 KDM4E (0.42) CYP2C19ACHEPTPN1KDM4EL3MBTL1
SCHEMBL2448770 0.77 TNKS (0.40) KIF11
SCHEMBL9958210 0.76 KIF11 (0.37) KIF11PPARGPPARACYP2C19CYP2C9
SCHEMBL12560663 0.75 MAPK1 (0.48) CYP2C19CYP2C9ACHEKDM4EL3MBTL1
SCHEMBL9957605 0.75 NQO1 (0.47) CYP2C19CYP2C9KDM4ECYP1A2HPGD
SCHEMBL14600340 0.74 KIF11 (0.38) KIF11PPARGPPARACYP2C19CYP2C9
SCHEMBL1505829 0.74 ACHE (0.49) ACHEKDM4EL3MBTL1MAPTMAPK1
SCHEMBL5556584 0.73 CYP1A2 (0.47) CYP2C19CYP2C9KDM4EL3MBTL1CYP1A2
SCHEMBL14600418 0.73 KIF11 (0.38) KIF11PPARGPPARACYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-20050074631-A1 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2005-04-07 US disclosed