SCHEMBL9958210

SCHEMBL9958210

CC(C)(C)Oc1ccc(-c2c3ccccc3c(OB(O)O)c3ccccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.37
PPARG P37231 3/20 0.35
PPARA Q07869 3/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
PPARD Q03181 1/20 0.35
ACP1 P24666 1/20 0.33
PTPN1 P18031 1/20 0.32
RIPK1 Q13546 1/20 0.32
ACHE P22303 1/20 0.32
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5551744 0.83 ACHE (0.47) ACHEMAOB
SCHEMBL5551768 0.80 ACHE (0.41) ACHE
SCHEMBL5556127 0.79 MGLL (0.41) ACHE
SCHEMBL2447870 0.79 ACHE (0.38) ACHE
SCHEMBL9958054 0.77 PDE10A (0.43) CYP2C9CYP2C19
SCHEMBL5552228 0.76 ACHE (0.41) CYP2C19ACHE
SCHEMBL5551748 0.76 KIF11 (0.41) KIF11PPARGPPARACYP2C9CYP2C19
SCHEMBL5556622 0.76 DHODH (0.36) KIF11CYP2C9ACHE
SCHEMBL5555752 0.76 LPL (0.38) KIF11ACHE
SCHEMBL9958416 0.76 MAPT (0.38) CYP2C9CYP2C19ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed