SCHEMBL5552228

SCHEMBL5552228

OB(O)Oc1c2ccccc2c(-c2ccc(F)cc2)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPK14 Q16539 4/20 0.36
SERPINE1 P05121 1/20 0.35
PLA2G1B P04054 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
NR4A2 P43354 1/20 0.34
PRKAA2 P54646 1/20 0.34
PTGS2 P35354 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5556127 0.86 MGLL (0.41) ACHEKDM4EHPGDL3MBTL1ALDH1A1
SCHEMBL2447870 0.85 ACHE (0.38) ACHEKDM4EHPGDHTTNPSR1
SCHEMBL5551768 0.83 ACHE (0.41) ACHEKDM4EHTTNPSR1L3MBTL1
SCHEMBL5551744 0.80 ACHE (0.47) ACHEKDM4ECYP3A4HPGDALDH1A1
SCHEMBL5556622 0.79 DHODH (0.36) ACHENPSR1L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL5555752 0.79 LPL (0.38) ACHEHTTSMN1; SMN2MAPT
SCHEMBL9958416 0.79 MAPT (0.38) ACHEKDM4ECYP1A2CYP3A4HPGD
SCHEMBL30413770 0.77 ESR1 (0.41) CYP1A2CYP2C19ESR1GPR84
SCHEMBL1208752 0.77 ESR1 (0.41) CYP1A2CYP2C19ESR1GPR84
SCHEMBL26813573 0.77 ACHE (0.45) ACHEKDM4ECYP1A2CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-20050074631-A1 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2005-04-07 US disclosed