Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.66 |
| ▸ | CTSK | P43235 | 2/20 | 0.66 |
| ▸ | CTSL | P07711 | 1/20 | 0.66 |
| ▸ | REN | P00797 | 6/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | CCKBR | P32239 | 4/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556766 | 0.89 | CTSS (0.69) | CTSSCTSKCTSLRENCCKBR | |
| SCHEMBL5556732 | 0.89 | CTSS (0.69) | CTSSCTSKCTSLRENCCKBR | |
| SCHEMBL5556628 | 0.84 | CTSS (0.76) | CTSSCTSKCTSLMMP2MMP9 | |
| SCHEMBL5552378 | 0.83 | CTSS (0.64) | CTSSCTSKRENMMP2MMP9 | |
| SCHEMBL6021385 | 0.83 | CTSS (0.77) | CTSSCTSKCTSLMMP2MMP9 | |
| SCHEMBL5556975 | 0.82 | MMP2 (0.56) | CTSSCTSKCTSLMMP2MMP9 | |
| SCHEMBL999047 | 0.82 | CTSS (0.76) | CTSSCTSKCTSLMMP2MMP9 | |
| SCHEMBL3599165 | 0.82 | CTSS (0.76) | CTSSCTSKCTSLMMP2MMP9 | |
| SCHEMBL29908025 | 0.82 | CTSS (0.76) | CTSSCTSKCTSLMMP2MMP9 | |
| SCHEMBL29828648 | 0.82 | CTSS (0.76) | CTSSCTSKCTSLMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
| WO-2005027856-A2 | INHIBITORS OF ANTHRAX LETHAL FACTOR | CENGENT THERAPEUTICS (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | CTSS 596/4885CTSK 306/4885CTSL 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.