Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 11/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12812342 | 0.86 | HCRTR2 (0.42) | CALCRLHPGDNOTUMHCRTR2 | |
| SCHEMBL1434918 | 0.82 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL5552182 | 0.82 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL30663898 | 0.77 | RBP4 (0.47) | CALCRLHPGDNOTUMHCRTR2 | |
| SCHEMBL12812347 | 0.77 | HCRTR2 (0.41) | CALCRLHCRTR2 | |
| SCHEMBL1434919 | 0.77 | DRD2 (0.41) | CALCRL | |
| SCHEMBL12812343 | 0.76 | NAMPT (0.41) | CALCRLHCRTR2 | |
| SCHEMBL12812349 | 0.75 | HPGD (0.48) | CALCRLHPGD | |
| SCHEMBL5553762 | 0.74 | CA1 (0.43) | CALCRLHCRTR2 | |
| SCHEMBL12812368 | 0.73 | HCRTR2 (0.41) | CALCRLHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1804919-A2 | CGRP RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006047196-A2 | CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2006-05-04 | — | — | WO | disclosed |