Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.48 |
| ▸ | CTSD | P07339 | 9/20 | 0.46 |
| ▸ | CTSE | P14091 | 9/20 | 0.46 |
| ▸ | BACE1 | P56817 | 5/20 | 0.44 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.42 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053513 | 0.91 | NMUR2 (0.47) | NMUR2NMUR1 | |
| SCHEMBL4464636 | 0.85 | APLNR (0.54) | — | |
| SCHEMBL4464498 | 0.85 | PSMB5 (0.49) | ACE | |
| SCHEMBL2760995 | 0.84 | PSMB5 (0.49) | OPRK1 | |
| SCHEMBL5068397 | 0.83 | F2 (0.54) | — | |
| SCHEMBL5049036 | 0.82 | PSMB5 (0.46) | BACE1 | |
| SCHEMBL7619215 | 0.81 | NMUR2 (0.58) | NMUR2NMUR1OPRK1 | |
| SCHEMBL3487862 | 0.79 | FAAH (0.44) | — | |
| SCHEMBL4459179 | 0.78 | APLNR (0.63) | — | |
| SCHEMBL29630391 | 0.78 | ACE (0.55) | ACEACE2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750745-A1 | METHODS OF INHIBITING PROINFLAMMATORY CYTOKINE EXPRESSION USING GHRELIN | The United States of America, represented by the Secretary, Department of Health and Human Services (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110463-A1 | METHODS OF INHIBITING PROINFLAMMATORY CYTOKINE EXPRESSION USING GHRELIN | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (US) | 2005-11-24 | — | — | WO | disclosed |