SCHEMBL5554116

SCHEMBL5554116

CCCCCCCCCCCCC1=C(O)C(=O)C=CC1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 18/20 0.62
MPEG1 Q2M385 11/20 0.62
XIAP P98170 2/20 0.62
GPR84 Q9NQS5 2/20 0.62
KDM4E B2RXH2 1/20 0.62
MEN1 O00255 1/20 0.62
PTGES O14684 1/20 0.62
USP2 O75604 1/20 0.62
ALDH1A1 P00352 1/20 0.62
TP53 P04637 1/20 0.62
CYP2D6 P10635 1/20 0.62
MAPT P10636 1/20 0.62
CYP2C9 P11712 1/20 0.62
HPGD P15428 1/20 0.62
ALOX15 P16050 1/20 0.62
ALOX12 P18054 1/20 0.62
MAPK1 P28482 1/20 0.62
CYP2C19 P33261 1/20 0.62
KMT2A Q03164 1/20 0.62
KAT2B Q92831 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27904845 1.00 ALOX5 (0.62) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL932791 0.92 ALOX5 (0.51) ALOX5MPEG1XIAPGPR84KDM4E
Hydrochloric Acid SCHEMBL28922225 0.84 ACHE (0.57) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL28655350 0.83 ACHE (0.55) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL6754258 0.78 ACHE (0.50) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL8933270 0.77 ACHE (0.50) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL21814597 0.77 ACHE (0.50) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL21814670 0.77 ACHE (0.50) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL21814489 0.77 ACHE (0.50) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL21814615 0.77 ACHE (0.50) ALOX5MPEG1XIAPGPR84KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160658-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2007-01-09 US disclosed
US-6936388-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2005-08-30 US disclosed
US-20050170272-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2005-08-04 US disclosed
US-20030077531-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2003-04-24 US disclosed