Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929703 | 0.91 | OPRK1 (0.38) | KDM4EALDH1A1PPARGKMT2ASMN1; SMN2 | |
| SCHEMBL927097 | 0.87 | KDM4E (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL5556431 | 0.80 | SLC9A1 (0.40) | KDM4CKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL928060 | 0.80 | CNR1 (0.38) | CNR1CNR2 | |
| SCHEMBL7913336 | 0.77 | ALDH1A1 (0.32) | KDM4CKDM4EALDH1A1PPARGKMT2A | |
| SCHEMBL5556439 | 0.77 | SLC9A1 (0.36) | KDM4CKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2003927 | 0.76 | — | — | |
| SCHEMBL926544 | 0.75 | — | — | |
| SCHEMBL926545 | 0.75 | — | — | |
| SCHEMBL927320 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849774-A1 | CYCLOHEPTA(b)PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME | TOA EIYO LTD. (JP) | 2007-10-31 | — | — | EP | disclosed |