Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556466 | 0.79 | PTGDR2 (0.45) | ALDH1A1KMT2AMAPTSMN1; SMN2PTGDR2 | |
| SCHEMBL7364397 | 0.75 | HDAC1 (0.57) | ALDH1A1MAPTKDM4ESMN1; SMN2PTGDR2 | |
| SCHEMBL3168541 | 0.75 | PTGDR2 (0.44) | ALDH1A1KMT2AMAPTSMN1; SMN2PTGDR2 | |
| SCHEMBL6191976 | 0.74 | EGFR (0.46) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5556417 | 0.73 | PTGDR2 (0.41) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6153749 | 0.73 | KMT2A (0.49) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL3169884 | 0.73 | MTNR1B (0.55) | ALDH1A1GAASMN1; SMN2HPGDLMNA | |
| SCHEMBL7368226 | 0.73 | CNR2 (0.57) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL5552521 | 0.71 | SMN1; SMN2 (0.71) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6345753 | 0.70 | CNR2 (0.53) | MEN1KMT2AMAPTGAAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
| WO-2005027856-A2 | INHIBITORS OF ANTHRAX LETHAL FACTOR | CENGENT THERAPEUTICS (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | ALDH1A1 4059/4885MEN1 3362/4885KMT2A 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.