Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.42 |
| ▸ | MMP1 | P03956 | 6/20 | 0.42 |
| ▸ | MMP3 | P08254 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 5/20 | 0.42 |
| ▸ | MMP8 | P22894 | 5/20 | 0.42 |
| ▸ | FCER2 | P06734 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552631 | 1.00 | MMP2 (0.42) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL5558824 | 0.92 | MMP2 (0.43) | MMP2MMP1MMP3PSEN1PSEN2 | |
| SCHEMBL5558426 | 0.89 | MMP1 (0.52) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL5552717 | 0.89 | MMP1 (0.52) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL5556802 | 0.82 | MMP2 (0.50) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL5557500 | 0.80 | MMP2 (0.47) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL5552331 | 0.80 | MMP2 (0.47) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL6245527 | 0.80 | MMP2 (0.47) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL5558074 | 0.77 | MMP2 (0.38) | MMP2MMP1MMP9MMP8FCER2 | |
| SCHEMBL5552411 | 0.75 | MMP1 (0.42) | MMP2MMP1MMP3MMP9IDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | MMP2 85/4885MMP1 950/4885MMP3 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.