Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084897 | 0.82 | PNMT (0.61) | PNMT | |
| SCHEMBL3586535 | 0.76 | PNMT (0.49) | PNMT | |
| SCHEMBL13984175 | 0.69 | — | — | |
| SCHEMBL31564654 | 0.63 | ALDH1A1 (0.39) | — | |
| SCHEMBL16869981 | 0.60 | PARP1 (0.43) | — | |
| SCHEMBL9414836 | 0.60 | DRD2 (0.43) | — | |
| SCHEMBL31564089 | 0.60 | DRD2 (0.43) | — | |
| SCHEMBL930203 | 0.60 | KCNQ2 (0.31) | PNMT | |
| SCHEMBL31563899 | 0.60 | DRD2 (0.43) | — | |
| SCHEMBL21236155 | 0.60 | PNMT (0.63) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778243-A2 | SUBSTITUTED AZEPINE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | Athersys, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006004931-A2 | SUBSTITUTED AZEPINE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS, INC. (US) | 2006-01-12 | — | — | WO | disclosed |