Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986203 | 0.83 | ALDH1A1 (0.32) | CYSLTR1 | |
| SCHEMBL13862514 | 0.81 | KMT2A (0.44) | — | |
| SCHEMBL17578357 | 0.81 | CA2 (0.33) | CA2NAMPT | |
| SCHEMBL16995240 | 0.81 | NAMPT (0.30) | NAMPT | |
| SCHEMBL12831690 | 0.81 | NAMPT (0.30) | NAMPT | |
| SCHEMBL8221693 | 0.79 | KEAP1 (0.38) | CYSLTR1CA2ITGB3ITGA2BPOLB | |
| SCHEMBL18468549 | 0.78 | TDP1 (0.33) | — | |
| SCHEMBL23349282 | 0.76 | HSP90AB1 (0.39) | — | |
| SCHEMBL19888619 | 0.76 | CYP1A2 (0.36) | — | |
| SCHEMBL19888586 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4367285-A | Assaying lipid peroxide in lipid compositions | TOYO JOZO COMPANY, LTD. (JP) | 1983-01-04 | — | — | US | claimed |
| EP-3752497-B1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-116854690-A | Indole uncaria alkaloid substance extraction method and application thereof | 河南中医药大学 | 2023-10-10 | — | — | CN | disclosed |
| WO-2023146809-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-115812671-A | Method for establishing animal model of Parkinson's disease and application thereof | 青岛大学 | 2023-03-21 | — | — | CN | disclosed |
| US-20230025707-A1 | Anti-Alpha-Synuclein Monoclonal Antibodies, and Methods Using Same | UNIV PENNSYLVANIA (US) | 2023-01-26 | — | — | US | disclosed |
| EP-4061840-A1 | ANTI-ALPHA-SYNUCLEIN MONOCLONAL ANTIBODIES, AND METHODS USING SAME | The Trustees of The University of Pennsylvania (US) | 2022-09-28 | — | — | EP | disclosed |
| CN-114945592-A | Anti-alpha-synuclein monoclonal antibodies and methods of use thereof | 宾夕法尼亚大学董事会 | 2022-08-26 | — | — | CN | disclosed |
| CN-113433239-A | Marker and kit for diagnosing cardia cancer | 郑州大学第一附属医院 | 2021-09-24 | — | — | CN | disclosed |
| WO-2021102197-A1 | ANTI-ALPHA-SYNUCLEIN MONOCLONAL ANTIBODIES, AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2021-05-27 | — | — | WO | disclosed |
| WO-2000020423-A1 | TRICYCLIC Δ3-PIPERIDINES AS PHARMACEUTICALS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000020421-A2 | TRICYCLIC Δ3-PIPERIDINES AS α2-ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-04-13 | — | — | WO | disclosed |
| WO-1998045297-A1 | 1,2,3,4-TETRAHYDRO-BENZOFURO[3,2-c]PYRIDINE DERIVATIVES__ | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-10-15 | — | — | WO | disclosed |
| EP-0630250-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING MONOSIALOGANGLIOSIDE GM 1? OR A DERIVATIVE THEREOF SUITABLE FOR THE TREATMENT OF PARKINSON'S DISEASE | FIDIA S.p.A. (IT) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993017691-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING MONOSIALOGANGLIOSIDE GM1 OR A DERIVATIVE THEREOF SUITABLE FOR THE TREATMENT OF PARKINSON'S DISEASE | FIDIA S.P.A. (IT) | 1993-09-16 | — | — | WO | disclosed |
| US-5231104-A | Anticholinergic | PFIZER INC. (US) | 1993-07-27 | — | — | US | disclosed |
| US-4531008-A | Insecticide, miticide | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-07-23 | — | — | US | disclosed |
| US-4376765-A | Medicaments, their preparation and compositions containing same | INSTITUT INTERNATIONAL DE PATHOLOGIE CELLULAIRE ET MOLECULAIRE (BE) | 1983-03-15 | — | — | US | disclosed |
| EP-0037388-A2 | Pharmaceutical forms, their preparation and compositions containing the same | INSTITUT INTERNATIONAL DE PATHOLOGIE CELLULAIRE ET MOLECULAIRE (BE) | 1981-10-07 | — | — | EP | disclosed |
| US-4098881-A | COMPOSITIONS TO CONTROL THE CHRONIC EFFECTS OF EXPOSURE TO SUNLIGHT COMPRISING CONJUGATED DIENES | THE PROCTER & GAMBLE COMPANY (US) | 1978-07-04 | — | — | US | disclosed |