Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 5/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 4/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.34 |
| ▸ | KLK1 | P06870 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP8 | P22894 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.31 |
| ▸ | GHSR | Q92847 | 2/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552747 | 0.83 | MMP2 (0.46) | MMP3MMP2MMP1MMP9MMP8 | |
| SCHEMBL5557731 | 0.83 | KLKB1 (0.42) | MMP3MMP2MMP1KLKB1KLK1 | |
| SCHEMBL5552457 | 0.82 | KLKB1 (0.44) | MMP3MMP2MMP1KLKB1KLK1 | |
| SCHEMBL5556372 | 0.82 | KLKB1 (0.44) | MMP3MMP2MMP1KLKB1KLK1 | |
| SCHEMBL5557724 | 0.81 | KLKB1 (0.36) | MMP3MMP2MMP1KLKB1KLK1 | |
| SCHEMBL5556679 | 0.81 | KLKB1 (0.44) | MMP3MMP2MMP1KLKB1KLK1 | |
| SCHEMBL5552392 | 0.79 | KLKB1 (0.36) | MMP3MMP2MMP1KLKB1KLK1 | |
| SCHEMBL5556531 | 0.79 | MMP2 (0.43) | MMP3MMP2MMP1KLKB1KLK1 | |
| SCHEMBL5556605 | 0.79 | MMP2 (0.47) | MMP3MMP2MMP1KLKB1KLK1 | |
| SCHEMBL5552593 | 0.74 | CTSS (0.55) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | MMP3 327/4885MMP2 85/4885MMP1 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.