SCHEMBL555854

SCHEMBL555854

NCCCC[C@H](N)C(=O)C1=CC(=O)NC1=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.43
DPP7 Q9UHL4 7/20 0.38
DPP9 Q86TI2 4/20 0.38
DPP8 Q6V1X1 3/20 0.38
TERT O14746 5/20 0.36
MMP2 P08253 1/20 0.35
LTA4H P09960 1/20 0.34
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
CHEK1 O14757 1/20 0.33
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL555856 1.00 GSR (0.43) GSRDPP7DPP9DPP8TERT
Lysine SCHEMBL28207112 0.70 GSR (0.67) GSRDPP7DPP9DPP8MMP2
Lysine SCHEMBL3868637 0.70 GSR (0.67) GSRDPP7DPP9DPP8MMP2
SCHEMBL30341824 0.67 GSR (0.52) GSRDPP7DPP9DPP8TERT
SCHEMBL28992842 0.66 GSR (0.55) GSRDPP7DPP9DPP8TERT
SCHEMBL9631019 0.66 GSR (0.55) GSRDPP7DPP9DPP8TERT
SCHEMBL9315967 0.65 GSR (0.48) GSRDPP7DPP9DPP8MMP2
SCHEMBL555855 0.65 DPP7 (0.51) GSRDPP7DPP9DPP8DPP4
Lysine SCHEMBL29075874 0.65 GSR (0.95) GSR
SCHEMBL6022461 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2398498-B1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN OX40 UCB BIOPHARMA SPRL (BE) 2018-09-05 EP claimed
EP-3339325-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB Biopharma SPRL (BE) 2018-06-27 EP claimed
US-9957328-B2 Bacterial host strain expressing recombinant DSBC UCB PHARMA, S.A. (GB) 2018-05-01 US claimed
US-20170335003-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC CELLTECH R&D LTD. (GB) 2017-11-23 US claimed
EP-2731973-B1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB BIOPHARMA SPRL (BE) 2017-11-15 EP claimed
US-9725516-B2 Bacterial host strain expressing recombinant DSBC UCB PHARMA, S.A. (BE) 2017-08-08 US claimed
US-20140141468-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB PHARMA, S.A. (BE) 2014-05-22 US claimed
EP-2731973-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB Pharma, S.A. (BE) 2014-05-21 EP claimed
US-8614295-B2 Antibody molecules having specificity for human OX40 UCB PHARMA S.A. (BE) 2013-12-24 US claimed
US-20130330344-A1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN OX40 UCB PHARMA S.A. (BE) 2013-12-12 US claimed
US-20050181448-A1 Biological products UCB S.A. (BE) 2005-08-18 US claimed
CN-1568331-A Biological products CELLTECH R&D LTD (GB) 2005-01-19 CN claimed
WO-2004072116-A2 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN IL-1β CELLTECH R & D LIMITED (GB) 2004-08-26 WO claimed
EP-1438340-A2 ANTIBODIES AGAINST KDR, THEIR PRODUCTION AND USES Celltech R & D Limited (GB) 2004-07-21 EP claimed
US-20030157061-A1 Combinations of a cyclooxygenase-2 selective inhibitor and a TNFalpha antagonist and therapeutic uses therefor PHARMACIA CORPORATION (US) 2003-08-21 US claimed
WO-2003031475-A2 ANTIBODIES AGAINST KDR, THEIR PRODUCTION AND USES CELLTECH R & D LIMITED (GB) 2003-04-17 WO claimed
EP-1287140-A1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN TUMOR NECROSIS FACTOR ALPHA, AND USE THEREOF Celltech R&D Limited (GB) 2003-03-05 EP claimed
US-20030026805-A1 Biological products UCB S.A. (BE) 2003-02-06 US claimed
US-20020151682-A1 Biological products UCB S.A. (BE) 2002-10-17 US claimed
WO-2001094585-A1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN TUMOR NECROSIS FACTOR ALPHA, AND USE THEREOF CELLTECH R & D LIMITED (GB) 2001-12-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130330344-A1 ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN OX40 LY96, IGSF11, FCGR1A GSR 4729/4885DPP7 4445/4885DPP9 4018/4885
US-20030157061-A1 Combinations of a cyclooxygenase-2 selective inhibitor and a TNFalpha antagonist and therapeutic uses therefor TNF, TNFRSF1A, CD40 GSR 759/4885DPP7 1077/4885DPP9 2844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.