Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423511 | 1.00 | ELANE (0.37) | ELANECNR1CNR2MGLLPOLB | |
| SCHEMBL5797107 | 0.91 | LMNA (0.40) | ELANEMEN1KMT2ASMN1; SMN2PTGS2 | |
| SCHEMBL5801111 | 0.91 | CNR1 (0.36) | ELANECNR1CNR2POLBMEN1 | |
| SCHEMBL5801105 | 0.91 | CNR1 (0.36) | ELANECNR1CNR2POLBMEN1 | |
| SCHEMBL5798158 | 0.91 | ELANE (0.41) | ELANECNR1CNR2MGLLPOLB | |
| SCHEMBL5560746 | 0.90 | ELANE (0.37) | ELANECNR1CNR2MGLLPOLB | |
| SCHEMBL5797099 | 0.89 | PTGS2 (0.40) | PTGS2 | |
| SCHEMBL5797617 | 0.89 | CNR1 (0.38) | ELANECNR1CNR2POLBMEN1 | |
| SCHEMBL5560484 | 0.89 | TSHR (0.35) | MGLLPTGS2 | |
| SCHEMBL5797616 | 0.89 | CNR1 (0.38) | ELANECNR1CNR2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643961-A4 | COX-2 AND FAAH INHIBITORS | MICROBIA INC (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |
| EP-1643961-A2 | COX-2 AND FAAH INHIBITORS | Microbia, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005002525-A2 | COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2005-01-13 | — | — | WO | disclosed |