SCHEMBL5559192

SCHEMBL5559192

CC(C)COC1(OCC(C)C)CCC(C)(C)N(OC(C)c2ccccc2)C1(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.32
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31
OPRL1 P41146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4984507 0.78 NPSR1 (0.33) NPSR1
SCHEMBL682099 0.75 CYP2D6 (0.36) OPRM1OPRD1OPRK1OPRL1
SCHEMBL17852271 0.73 OPRM1 (0.37) OPRM1OPRD1OPRK1OPRL1
SCHEMBL5560215 0.73
SCHEMBL5565682 0.71 OPRM1 (0.30) OPRM1OPRD1OPRK1OPRL1
SCHEMBL28479357 0.70 CYP2D6 (0.37) NPSR1OPRM1OPRD1OPRK1OPRL1
SCHEMBL5564952 0.69 OPRM1 (0.38) NPSR1OPRM1OPRD1OPRK1OPRL1
SCHEMBL15854882 0.68 OPRM1 (0.40) OPRM1OPRD1OPRK1OPRL1
SCHEMBL3388839 0.67 MEN1 (0.43)
SCHEMBL8853589 0.67 HPGD (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288613-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, their corresponding N-oxides and controlled radical polymerization therewith CIBA SPECIALTY CHEMICALS CORP. (US) 2007-10-30 US disclosed
US-20060149011-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, their corresponding N-oxides and controlled radical polymerization therewith NESVADBA PETER 2006-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060149011-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, their corresponding N-oxides and controlled radical polymerization therewith ALKBH2, ALKBH3, ALKBH5 NPSR1 2452/4885OPRM1 14/4885OPRD1 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.