Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565406 | 0.77 | L3MBTL1 (0.30) | — | |
| SCHEMBL4981929 | 0.76 | — | — | |
| SCHEMBL682099 | 0.73 | CYP2D6 (0.36) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4981000 | 0.71 | OPRD1 (0.31) | OPRD1 | |
| SCHEMBL6031838 | 0.71 | — | — | |
| SCHEMBL5559192 | 0.71 | NPSR1 (0.32) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17852271 | 0.68 | OPRM1 (0.37) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5337816 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL5564952 | 0.66 | OPRM1 (0.38) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6032195 | 0.66 | TACR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288613-B2 | N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, their corresponding N-oxides and controlled radical polymerization therewith | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-10-30 | — | — | US | disclosed |
| US-20060149011-A1 | N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, their corresponding N-oxides and controlled radical polymerization therewith | NESVADBA PETER | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149011-A1 | N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, their corresponding N-oxides and controlled radical polymerization therewith | ALKBH2, ALKBH3, ALKBH5 | OPRM1 14/4885OPRD1 6/4885OPRK1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.