SCHEMBL5559244

SCHEMBL5559244

CN(C)c1c(N)ncnc1N

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ NUDT1 P36639 1/20 0.44
▸ ADK P55263 7/20 0.37
▸ LRRK2 Q5S007 3/20 0.37
▸ ADORA2A P29274 1/20 0.35
▸ ADORA1 P30542 1/20 0.35
▸ PI4KA P42356 5/20 0.34
▸ PI4K2B Q8TCG2 5/20 0.34
▸ PI4K2A Q9BTU6 5/20 0.34
▸ PI4KB Q9UBF8 5/20 0.34
▸ LIMK1 P53667 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ XDH P47989 2/20 0.33
▸ CHEK1 O14757 1/20 0.33
▸ AURKA O14965 1/20 0.33
▸ RET P07949 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18312090 0.85 NUDT1 (0.39) NUDT1ADKLRRK2ADORA2AADORA1
SCHEMBL2316376 0.72 CHEK1 (0.42) NUDT1ADKLRRK2ADORA2AADORA1
SCHEMBL18520322 0.68 NUDT1 (0.31) NUDT1LIMK1L3MBTL1
Hydrochloric Acid SCHEMBL7053218 0.67 NOS2 (0.54) LIMK1L3MBTL1AURKA
SCHEMBL7519562 0.67 — —
SCHEMBL8856393 0.67 CHEK1 (0.47) NUDT1LRRK2CHEK1AURKALMNA
SCHEMBL2942472 0.66 IP6K1 (0.41) —
SCHEMBL25593925 0.66 NOS3 (0.41) NUDT1ADKLRRK2ADORA2AADORA1
SCHEMBL1718947 0.65 — —
SCHEMBL28483237 0.65 DGAT1 (0.38) NUDT1ADKLRRK2PI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110305125-A 5- pyrimidine -6- oxygen-Pyrazolopyridine analog derivative and its preparation method and application 中南大学 2019-10-08 — — CN claimed
EP-0667557-B1 Grain growth process for the preparation of high bromide ultrathin tabular grain emulsions EASTMAN KODAK CO (US) 2001-11-14 — — EP claimed
US-6228573-B1 IN PRESENCE OF TRIAMINOPYRIMIDINE EASTMAN KODAK COMPANY 2001-05-08 — — US claimed
JP-2935568-B2 — — 1999-08-16 — — JP claimed
EP-0558734-B1 PROCESS FOR THE PREPARATION OF HIGH CHLORIDE TABULAR GRAIN EMULSIONS (IV) EASTMAN KODAK CO (US) 1997-03-12 — — EP claimed
EP-0667557-A2 Grain growth process for the preparation of high bromide ultrathin tabular grain emulsions EASTMAN KODAK COMPANY (US) 1995-08-16 — — EP claimed
US-5411851-A Crystallization for silver halide emulsions from dispersion and triaminopyrimidine compounds for control of size EASTMAN KODAK COMPANY (US) 1995-05-02 — — US claimed
EP-0558734-A1 PROCESS FOR THE PREPARATION OF HIGH CHLORIDE TABULAR GRAIN EMULSIONS (IV). EASTMAN KODAK CO (US) 1993-09-08 — — EP claimed
WO-1993006522-A1 PROCESS FOR THE PREPARATION OF HIGH CHLORIDE TABULAR GRAIN EMULSIONS (IV) EASTMAN KODAK COMPANY (US) 1993-04-01 — — WO claimed
US-7179885-B2 Silver-dispersing polypeptides FUJI PHOTO FILM B.V. (NL) 2007-02-20 — — US disclosed
US-20040048208-A1 Silver-dispersing polypeptides FUJI FILM MANUFACTURING EUROPE B.V. (NL) 2004-03-11 — — US disclosed
EP-1356350-A1 SILVER-DISPERSING POLYPEPTIDES Fuji Photo Film B.V. (NL) 2003-10-29 — — EP disclosed
WO-2002052342-A1 SILVER-DISPERSING POLYPEPTIDES FUJI PHOTO FILM B.V. (NL) 2002-07-04 — — WO disclosed
US-6228573-B1 IN PRESENCE OF TRIAMINOPYRIMIDINE EASTMAN KODAK COMPANY 2001-05-08 — — US disclosed
EP-0670514-A2 High chloride (100) tabular grain emulsions with modified edge structures EASTMAN KODAK COMPANY (US) 1995-09-06 — — EP disclosed
EP-0667557-A2 Grain growth process for the preparation of high bromide ultrathin tabular grain emulsions EASTMAN KODAK COMPANY (US) 1995-08-16 — — EP disclosed
EP-0577173-A1 High-chloride folded tabular grain emulsions and process for their preparation EASTMAN KODAK COMPANY (US) 1994-01-05 — — EP disclosed
EP-0558734-A1 PROCESS FOR THE PREPARATION OF HIGH CHLORIDE TABULAR GRAIN EMULSIONS (IV). EASTMAN KODAK CO (US) 1993-09-08 — — EP disclosed
WO-1993006522-A1 PROCESS FOR THE PREPARATION OF HIGH CHLORIDE TABULAR GRAIN EMULSIONS (IV) EASTMAN KODAK COMPANY (US) 1993-04-01 — — WO disclosed
EP-0534325-A1 Ultrathin high chloride tabular grain emulsions EASTMAN KODAK COMPANY (US) 1993-03-31 — — EP disclosed
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