Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | GRB2 | P62993 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12128833 | 0.78 | CYP1A2 (0.47) | TPH1CYP1A2HSD17B10SLC7A5PTGS1 | |
| SCHEMBL13957329 | 0.78 | CYP1A2 (0.47) | TPH1CYP1A2HSD17B10SLC7A5PTGS1 | |
| SCHEMBL5567186 | 0.78 | CYP1A2 (0.46) | TPH1CYP1A2HSD17B10SLC7A5PTGS1 | |
| SCHEMBL7205029 | 0.76 | SLC7A5 (0.56) | CYP1A2HSD17B10ESR1ESR2SLC7A5 | |
| SCHEMBL5283089 | 0.76 | SLC7A5 (0.56) | CYP1A2HSD17B10ESR1ESR2SLC7A5 | |
| SCHEMBL15360000 | 0.76 | CYP1A2 (0.49) | TPH1CYP1A2HSD17B10SLC7A5PTGS1 | |
| SCHEMBL6024170 | 0.76 | SLC7A5 (0.61) | TPH1CYP1A2HSD17B10ESR1SLC7A5 | |
| SCHEMBL18571041 | 0.76 | SLC7A5 (0.47) | TPH1CYP1A2HSD17B10SLC7A5PTGS1 | |
| SCHEMBL5565798 | 0.76 | SLC7A5 (0.47) | TPH1CYP1A2HSD17B10SLC7A5PTGS1 | |
| SCHEMBL13957328 | 0.76 | SLC7A5 (0.47) | TPH1CYP1A2HSD17B10SLC7A5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189383-B2 | Radioactively labelled amino acid analogues, their preparation and use | MALLINCKRODT INC. | 2007-03-13 | — | — | US | claimed |
| US-20060127306-A1 | Radioactively labelled amino acid analogues, their preparation and use | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2006-06-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060127306-A1 | Radioactively labelled amino acid analogues, their preparation and use | BCAT1, BCAT2, SLC1A5 | TPH1 424/4885CYP1A2 150/4885HSD17B10 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.